Tuesday, November 25, 2014

Be humble, Be yourself



Most fundamental trait which makes a good learner is humility.  And learning is a lifelong process. Day you stop being humble enough to receive, that day your influx of wisdom and knowledge slows down.   Probably, this is the reason in ancient times, Indian gurukuls made even princes beg for alms to learn humility.    If you are too full of yourself, there is no space for new knowledge or wisdom to enter.  Sometimes, I feel we were born humble, we acquire pride on the way, but life in itself manages to give you a lesson in humility. As C.S. Lewis said, “Humility is not thinking less of yourself, it’s thinking of yourself less.”

Potential Treatment for Alzheimer Disease

Burgess et al present intriguing results of repetitive transient opening of the blood-brain barrier (BBB) in a transgenic mouse model of advanced Alzheimer disease (AD). The results underscore the potential of using magnetic resonance (MR) imaging–guided focused ultrasound and microbubble ultrasonography (US) contrast agents for the disruption of the BBB as a potential long-term therapy to reduce amyloid plaque burden and improve cognitive performance.

Reference: 
Science to Practice: Opening the Blood-Brain Barrier with Focused Ultrasound—A Potential Treatment for Alzheimer Disease? Ferenc A. Jolesz. Radiology 2014 273:3 , 631-633 

Tuesday, November 18, 2014

Tennis Leg- MRI

Increased signal and fluid in relation to the medial head of gastrocnemius muscle with fluid deep to muscle belly between gastrocnemius and soleus. There is proximal retraction of muscle belly along with fluid signal in the myotendinous junction suggesting tear of the medial gastrocnemius.

 MRI findings of tennis leg include: 
1) high T2 signal fluid deep to medial gastrocnemius and superficial to the soleu
2) focal area of disruption of muscle continuity noted along the deep aspect of the medial head of the gastrocnemius, with associated oedema of the muscle






Heel Fat Pad Syndrome

Patient with heel pain shows: Altered signal in the heel fat pad with hypointense signal on T1 weighted images and hyperintense on STIR images. These findings likely heel fat pad syndrome or inflammation.


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